Which model leads ProteinGym Hard?

Claude Mythos 5.1 leads the ProteinGym Hard board of 6 measured models on the Vector Wire tracker at 49.3. Every score is source-attributed with a verification tier.

ProteinGym Hard Leaderboard — Model Scores

Refresh Models —Deals —Regulatory —Sources —

Pro Mode — raw scores, one benchmark under the lensofficial card harness

The field · 6 measured

35.549.3

6 models measured, most on the official card harness. Claude Mythos 5.1 tops the board at 49.3.

6 measured·6 new this week·Lifecycle Updated Sep 2, 2026Basis

#◆Vendor$/M in$/M out

Leader — ignites whiteField — fill cools with scoreIndependently verified only0 of 6Bars show 35.5–49.3· ◆ solid = first-party or better · outlined = arm's-length

01Claude Mythos 5.1NEWAnthropic49.3———

02Claude Opus 5NEW+3 altsAnthropic47.7$5.0/M$25.0/M$0.314

03Claude Mythos 5NEWAnthropic45.8———

04Gemini 3.1 ProNEWGoogle37$2.0/M$12.0/M$0.189

05Claude Sonnet 5NEWAnthropic36.6$2.0/M$10.0/M$0.164

06GPT-5.6 SolNEWOpenAI35.5$4.0/M$20.0/M$0.338

◆ solid = independently verified · aggregator attested · vendor attributed — outlined = cross-reference · source-attributed. Dimmed ◆ = confidence inferred. “+N alts” = alternate disclosures in the drawer with why-demoted. Prices per million tokens; $/point = input price ÷ score. Every row opens its model dossier.